Zephaniah Alexander Looby (April 8, 1899 – March 24, 1972) was a lawyer in Nashville, Tennessee, who was active in the civil rights movement. Born in the British West Indies, he immigrated to the United States at the age of 15; he earned degrees at Howard University, Columbia University Law School and New York University.

He settled in Nashville, Tennessee, where he built a law practice and taught at Fisk University. He is noted for being part of the defense team for 25 black men charged in attempted murder for the Columbia race riot of 1946 and winning acquittals for most, in the aftermath of the first major racial confrontation in the United States after World War II. He participated in numerous other cases, including leading desegregation of schools in Nashville. He served as a Republican member of the Nashville City Council from 1951 to 1971. His house was bombed by segregationists on April 19, 1960.